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AAST - rVIIa
KMATTOX at aol.com KMATTOX at aol.comTue Oct 6 12:47:59 BST 2009
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In my view, the biggest thing to come out of the recent Amer Assoc Surgery of Trauma (AAST) meetings in Pittsburgh were TWO papers on analysis of studies of rVIIa in real people and analyzing the past publications. Each could have been labeled , "The rise and fall of rVIIa. The studies stated that basically there is no advantage of any kind that can be discovered from either of these two well designed studies. One was performed by one of the most respected researchers in blood, blood products, clotting, and resuscitation in the world. He stated that the entry criteria in the cases from the military were so poorly controlled, that no good statement could be made about just what the entry criteria should be to design a good study at this point in order to study this product. WOW. No different from the early Israeli studies of 13 years ago. If there was one observation that I could make is that maybe the TEG could have been a good instrument to determine which cases just might benefit from rVIIa to be given. k
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