Post Traumatic Coagulopathy vs DVT

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Actually early coagulopathy likely results in an increased likelihood of
DVT.  Early coagulopathy was identified by Peggy Knudson in the early
nineties as the strongest association with late DVT.  We have shown that
systemic activation of protein C is in part responsible for early
coagulopathy - early exhaustion of protein C may lead to a late
hypercoagulable state.  This association is yet to be fully investigated.
Karim

2009/6/22 Dr Timothy Hardcastle <dr.tchardcastle at absamail.co.za>

> Hi Ranjith
>
> Not to my knowledge - Trauma itself is a high risk factor for DVT. The
> coagulopathy reverses post resuscitation (usually after initial damage
> control) then the risk is still there!
>
> Tim
> Dr T C Hardcastle
> M.B., Ch.B. (Stell); M. Med. (Chir) (Stell); FCS (SA)
> Principal Specialist Trauma Surgeon /
> Honorary Lecturer University of KwaZulu-Natal Dept Surgery
> Deputy Director - IALCH Trauma Service
> Durban - South Africa
>
> > Does coagulopathy has any protection against DVT ?
> > Dr.Ranjith Ellawala
> > Trauma Unit,
> > Colombo
> > Sri Lanka
>
>
>
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