blunt traumatic arrest pharmacotherapy

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Pret, I must have missed all this evidence for the benefit of  
epinephrine last time I looked. As far as I know it is blessed by a  
century of tradition but no published study with clinically meaningful  
endpoints that shows benefit. Indeed there is a prehospital PRCT  
underway in Australia comparing epinephrine to saline for OHCA. Please  
let me know which new studies I have missed <grin>

Cheers, Ian

On 12/12/2009, at 1:37 AM, "Bjorn, Pret" <pbjorn at emh.org> wrote:
  On
> the contrary, there is long and fairly ample evidence to suggest that
> epinephrine has positive effects on resuscitating non-surgical
> pulselessness.
>
> outcome in these cases is (unsurprisingly)
> unflattering; but there has been no shortage of recent study  
> selectively
> exploiting epi's alpha2 properties (by pharmacologically blocking beta
> and alpha1 effects) with promising results.  In the near term, we're
> stuck with the whole drug; but it's difficult for any patient to  
> survive
> to discharge without ROSC; and for now, epi's one of the few drugs  
> known
> to get us there.
>
> Pret Bjorn, RN
> Bangor, ME USA
>
>>

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