Hyponatremia and Pneumothorax

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  The mechanism of SIADH induced by pnemothorax can be explained , theoretically, by the both chemical (hypoxia) and Mechanical (decreased pulmonary blood flow) that stimulate
  the volume receptor and baroreceptor in the left atrium, which thus regulate ADH release. The vasoconstriction caused by hypoxia may also influence left atrial
  blood filling. Some investigators have also reported that atrial natriuric polypeptide plays an important role in patients with SIADH .The increase in circulating
  blood volume caused by an inappropriate secretion of ADH induces atrial natriuric polypeptide secretion and thus results in urinary sodium excretion.
   
   
  SS
   
  Ref 
  A Syndrome of Inappropriate
  Secretion of Antidiuretic Hormone
  Associated with Pleuritis Caused
  by OK-432
  Takeshi Hanagiri
  Hiroyuki Muranaka
  Mitunori Hashimoto
  Akira Nagashima
  Department of Chest Surgery,
  Kitakyushu Municipal Medical Center,
  Kitakyushu, Japan
  OOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOO


bfletcher at columbus.rr.com wrote:  Has anyone ever seen a case of hyponatremia due to pneumothorax. Had a patient who developed profound hyponatremia without a reasonable cause (no head injury, meds etc). Has some rib fx, scap fx, transverse process fx and a Pneumothorax. 

When reviewing the literature, a cause of SIADH is pneumothorax. If so Why? Any ideas. 

Thanks
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