Progesterone in TBI?

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--- Forwarded Message ----
From: "Miller, Sanford" <Sanford.Miller at nyumc.org>
To: Ivan Hronek <ivanhronek at yahoo.com>
Sent: Monday, April 28, 2008 1:46:36 PM
Subject: RE: [ccm-l] any one see this article on Progesterone in TBI?

Very small study which, as they admit, says practically nothing, beyond
the likelihood that it doesn't help. Not truly randomised (77 treated,
23 placebo) and only a very few improved more than untreated pts. I
wonder if NIH will fund a full study after being burned by NASCIS. We'll
see. 

Sanford M. Miller, MD
sanford.miller at nyumc.org 

_______________________________

    From: Ivan Hronek [mailto:ivanhronek at yahoo.com] 
    Sent: Monday, April 28, 2008 12:38 PM
    To: Miller, Sanford
    Subject: Fw: [ccm-l] any one see this article on Progesterone in
TBI?
    
        
        Wright, D. W., Kellermann, A. L., Hertzberg, V. S.,
Clark, P. L., 
        Frankel, M., Goldstein, F. C., et. al. (2007). ProTECT:
a randomized 
        clinical trial of progesterone for acute traumatic brain
injury. Ann 
        Emerg Med, 49, 391-402.
        
        I've got a hard copy of this somewhere.
        
        Maybe we've been using the wrong steroid for brain
injury?
        
        ck
        Charles S. Krin, DO FAAFP 
        ________________________________

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