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Tue Jul 24 08:52:10 BST 2007

this an article I'd written a few years back on the subject, with its
accompanying editorial, and a trial which is being carried out to look into
the subject. I feel that vasopressin has certain advantages in patients who
dont respond to catecholamines after adequate volume resuscitation, the
important ones being an ability to act in severe metabolic acidosis, and an
apparent ability to resore the baroreceptor reflexes.that being said, it is
certainly not a substitute for achieving hemostasis
rangraj
On 7/24/07, Jacob Scholtz <jacob.scholz at gmail.com> wrote:
>
> After having read the thread about massive transfusion protocols I
> received
> an e-mail with the following article:
>
> Vasopressin improves survival in a porcine model of abdominal vascular
> injury
> Critical Care 2007, 11:R81 doi:10.1186/cc59772007, 11:R81 doi:10.1186
> /cc5977
> The authors conclude:
> "Vasopressin, but not fluid resuscitation or saline placebo, ensured
> short-term survival in this vascular injury model with uncontrolled
> haemorrhagic shock in sedated pigs."
>
> They were pigs and they were not transfused, but what does the list think
> about vasopressin, maybe in conjunction with transfusion, in human
> haemorrhagic shock?
>
> Jacob
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-- 
Lt Col Rangraj Setlur
Associate Professor
Department of Anaesthesiology and Critical Care
Armed Forces Medical College
Pune
India
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Vasopressin in haemorrhagic shock - Vasopressin vs Fluid