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Sat Jul 28 18:10:24 BST 2007

Ivan, curious if there's any information on neurogenic shock and vasopressin 
infusion's?

>From: IVAN HRONEK <ih7 at msn.com>
>Reply-To: "Trauma &amp; Critical Care mailing list" 
><trauma-list at trauma.org>
>To: "Trauma &amp; Critical Care mailing list" <trauma-list at trauma.org>
>Subject: RE: Vasopressin in haemorrhagic shock - Vasopressin vs Fluid
>Date: Sat, 28 Jul 2007 09:14:00 -0700
>
>Vasopressin during uncontrolled hemorrhagic shock: less bleeding below the 
>diaphragm, more perfusion above.Stadlbauer KH - Anesth Analg - 01-SEP-2005; 
>101(3): 830-2Vasopressin in hemorrhagic shock.Sharma RM - Anesth Analg - 
>01-SEP-2005; 101(3): 833-4, table of contentsWe describe the treatment of 
>two patients with hemorrhagic shock unresponsive to volume replacement and 
>catecholamines. Both patients responded to a small-dose infusion of 
>vasopressin, which allowed tapering off of the catecholamines. The possible 
>role of small-dose infusions of vasopressin in fluid- and 
>catecholamine-resistant hemorrhagic shock is discussed. Should the patients 
>be kept (after the initial phase) vasodilated with borderline pressure, or 
>vasoconstricted (vasopressin) with borderline pressure ?This would decrease 
>the amount of crystalloids that we overuse so much..and in this respect, 
>how about Ketamine instead of Fentanyl ?Ivan Hronek MDChief, Critical Care 
>& Trauma AnesthesiaSFMC Gas, Inc.St. Francis Medical Center3630 E. Imperial 
>HighwayLynwood, CA 90262 Cell: 310 487-3288Pager: 310 636-6020
>
> > Date: Tue, 24 Jul 2007 06:48:53 +0200> From: jacob.scholz at gmail.com> To: 
>trauma-list at trauma.org> Subject: Vasopressin in haemorrhagic shock - 
>Vasopressin vs Fluid> > After having read the thread about massive 
>transfusion protocols I received> an e-mail with the following article:> > 
>Vasopressin improves survival in a porcine model of abdominal vascular> 
>injury> Critical Care 2007, 11:R81 doi:10.1186/cc59772007, 11:R81 
>doi:10.1186/cc5977> The authors conclude:> "Vasopressin, but not fluid 
>resuscitation or saline placebo, ensured> short-term survival in this 
>vascular injury model with uncontrolled> haemorrhagic shock in sedated 
>pigs."> > They were pigs and they were not transfused, but what does the 
>list think> about vasopressin, maybe in conjunction with transfusion, in 
>human> haemorrhagic shock?> > Jacob> --> trauma-list : TRAUMA.ORG> To 
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