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plasma transfusion in hemorrhage

caesar ursic cmursic at gmail.com
Tue Jul 10 02:26:41 BST 2007


Thank you, Dr Hronek, this certainly does help.
CM Ursic, MD
Santa Fe
USA


On 7/9/07, IVAN HRONEK <ih7 at msn.com> wrote:
>
> Surgical Clinics of North America - Volume 87, Issue 1 (February 2007)
>
> Lessons learned from modern military surgery
> Alec C. Beekley, MD  ∗ Benjamin W. Starnes, MD James A. Sebesta, MD
>
> http://www.mdconsult.com/das/article/body/74311994-4/jorg=journal&source=MI&sp=16832942&sid=601500542/N/559408/1.html#h060014470306
>
> Excerpt:
> Borgman and colleagues demonstrated that increased number of stored RBC
> units transfused in the first 24 hours of admission was independently
> associated with decreased survival, whereas increased units of FFP
> transfused in the first 24 hours of admission was independently associated
> with improved survival. The median ratio of FFP:RBC was 1:1.7 in survivors
> compared with 1:3 in nonsurvivors (P<.001).
> In addition, 30% of survivors received recombinant factor VIIa compared
> with 16% of nonsurvivors, although this did not reach significance (P =
> .059).
> The use of component therapy in a ratio of 1:1 for RBC, FFP, and platelets
> is becoming the standard resuscitation regimen in some trauma centers.
> Baltimore Shock Trauma Center currently thaws fresh frozen plasma each
> morning, allowing for the immediate transfusion of fresh thawed plasma once
> a trauma patient requiring transfusions arrives.
>
> Hope this helps, there probably are more similar articles on MD
> Consult...Ivan Hronek MD
>
>
>
> > Date: Mon, 9 Jul 2007 13:20:15 -0600> From: cmursic at gmail.com> To:
> trauma-list at trauma.org> Subject: plasma transfusion in hemorrhage> > Does
> anyone have any references to published literature advocating> earlier/more
> frequent transfusion of plasma in serious hemorhagic shock or> bleeding? I
> found the article from the group in Houston ( Journal of> Trauma, Jan 2007,
> Gonzales, Moore Holcomb, et al), but I could swear there> have since been
> other studies published out of Iraq and elsewhere.> Thanks> CM Ursic, MD>
> Santa Fe> USA> --> trauma-list : TRAUMA.ORG> To change your settings or
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-- 
'Twas brillig, and the slithy toves
Did gyre and gimble in the wabe:
All mimsy were the borogoves,
And the mome raths outgrabe.


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