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Tue Jan 9 00:20:26 GMT 2007

l saw it few months ago and asked other docs on their opinion on the matter
but non said encouraging things especially if performing CPR in
out-of-hospital terms :(
but if someone out there has done it successfully for several occasions why
neglect that?
ante
2007/1/8, Jeff Hyland <jhylandmd at comcast.net>:
>
> Jago,
>
> Go to Pub Med and type in aminophylline and asystole.  Interesting data,
> keeping in mind that ROSC in no way implies successful cerebral
> resuscitation.
>
> Anecdotally (the best kind of evidence:))I have given it 3 times in 3
> years, and have had temporary ROSC once (eventual re-arrest and
> termination).  I do NOT routinely give this drug in an arrest.
>
> Interestingly, the European Resuscitation Council has it in their 2005
> guidelines (ref follows).  I cannot tell the indication from the
> abstract, but would assume they are referring to asystole.
> Anaesthesist. 2006 Sep;55(9):958-66, 968-72, 974-9.
>
> Aminophylline would not have a parasympathetic effect on the
> cardiovascular system.  On the contrary, it is a methylxanthine and
> would be expected to produce a sympathomimetic effect.
>
> Hope this helps.
>
> Regards,
>
> Jeff
>
> -----Original Message-----
> From: trauma-list-bounces at trauma.org
> [mailto:trauma-list-bounces at trauma.org] On Behalf Of Jago Miloguz
> Sent: Monday, January 08, 2007 10:09 AM
> To: Trauma &amp, Critical Care mailing list
> Subject: AMINOPHYLLINE IN REFRACTORY ASYSTOLE
>
> l apologize for not making it a trauma aspect directly,but nevertheless,
> it
> is not rare to have comorbidity of surgical and non-surgical conditions
> in
> same patient at the same time.
> so l was interested in hearing from first hands experiences if possible
> on
> use of aminophylline in asystole patients when adrenaline and atropine
> aren't doing it.
> the thing  that makes me hesitate is the fact that aminophylline would
> actually have a parasympathical effect on cardiovascular system
> they encourage usage due to its effect as a adenosine antagonist
> so l would appreciate any advise and your experiences
> regards, ante
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AMINOPHYLLINE IN REFRACTORY ASYSTOLE