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High Dose Mannitol

Coats Tim - Professor of Emergency Medicine Tim.Coats at uhl-tr.nhs.uk
Mon Jan 8 09:26:57 GMT 2007


I agree about the lessons for the co-authors and the journal's editorial
board which speak for themselves in the correspondence.

However, I have also taken a personal lesson from this, which is "Make
sure that others know where your past research data and records are
kept". I have all of my past research data, but I am not sure that if I
suddenly died today anyone else would know where to look for this
information. 

So my resolution for 2007 is to make sure that all my co-authors also
keep a copy of the data and to ensure that my system for storing
data/records is more obvious to anyone who in the future might be
looking for this information without my assistance.

As to the clinical implications of all this. I don't use high dose
mannitol, and it would now certainly take a good RCT with a positive
result to change my practice.

Tim. Coats.

-----Original Message-----
From: ICH32859 [mailto:usui-a at nifty.com] 
Sent: 06 January 2007 00:53
To: Trauma & Critical Care mailing list
Subject: RE: High Dose Mannitol



----- ??????? -----
???: "Bjorn, Pret" <pbjorn at emh.org>
??: "Trauma &amp; Critical Care mailing list" <trauma-list at trauma.org>
????: 07/01/05 23:26
??: RE: High Dose Mannitol

I don't think it's hard to understand what happened.  It's just
difficult to politely discuss.  

Credit where it's due: Cochrane's investigation of Dr. Cruz' research is
both tragically disparaging and strenuously fair.  Brilliant and
otherwise honorable people are not immune to profound ethical lapses,
especially when their core interests are at stake.  Either Dr. Cruz
fabricated research in the defense of his deep beliefs, or circumstances
have conspired to make it convincingly appear as such.

For myself, the most interesting part of CRASH2 message is the insight
it provides into research ethics and peer-review editorial standards.
In that respect the correspondences speak for themselves.  Cruz's
co-authors and the JoNS editorial board have much to regret.

Sad indeed.

Pret Bjorn, RN
Bangor, ME USA


-----Original Message-----
From: trauma-list-bounces at trauma.org
[mailto:trauma-list-bounces at trauma.org] On Behalf Of Rangraj Setlur
Sent: Thursday, January 04, 2007 10:20 AM
To: Trauma &amp, Critical Care mailing list





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