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Ketorolac
bensonblues at comcast.net bensonblues at comcast.netTue Aug 8 21:24:37 BST 2006
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Kim, The Physician's Desk Reference (USA) outlines contraindications for the use of ketorolac (bleeding or taking anticoagulants, suspected ICH, need for operation, hypovolemia, renal insufficiency, etc. Based upon its theoretic antiplatelet effects, negative effects on wound healing, and its well known renal effects, I see no role for ketorolac in any preop, postop, periop patient. The "Guy" from the UK is right on - they seem to be on the ball over there. I don't give it at all in my busy 90K visit ED, but my colleagues will argue that it is useful in renal colic because it decreaes ureteral peristalsis and renal blood flow. I say that giving ketorolac for renal colic is like giving a tocolytic to treat labor pains. This is a drug looking for an indication... DB
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