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Tue Dec 13 01:17:05 GMT 2005

Generic propoful has an effect on SBP that Diprivan has with much less effect. Low dose propoful (Diprivan) is amnestic and sedative but can allow the patient to be awake but unstressed. Diprivan is more consistant at low doses and anesthetic doses (approx. >50 mcg/Kg) during sedation with unstable patients then propoful generic.
Been there done that! Worked with Diprivan since it's introduction into this country in ICU as bedside RN.
Generic propoful requires higher doses to achieve the same level of sedation thereby affecting the SBP more. (Sulfites as the preservative, e/.g. similar to the lasix effect on BP)
 -------------- Original message ----------------------
From: Jedidiah Peterson <jedpeterson at gmail.com>
> While I am sure the American Society of Anesthesiologists and the American
> Association of Nurse Anesthetists are delighted to have your hearty
> endorsement, Statman, you might want to ease your rudder with regard to your
> assumptions about your fellow nurses and ER physicians...particularly in
> this forum.
> 
> You call the use of propofol in the ED "dangerous" but your specific
> concerns seem to be an RN who cannot manage an airway, an MD who abandons
> his post mid-procedure and a cardiac arrest with no MD to direct the
> resusitation effort.
> 
> Not a lofty, or particularly realistic, view of a modern emergency
> department.
> 
> You never mention the rapid effect on SBP, which is a more realistic
> concern, IMO, in a pre-hospital trauma setting where hemodynamics can be
> very dynamic indeed.
> 
> The fact remains that propofol is a very effective drug, that can be very
> beneficial to the patient when it is appropriately used. But it does come
> with a need for increased monitoring.
> 
> And if the anesthesiologist is the only one capable of such reponsibility,
> what happens if they get called away mid-procedure?
> 
> I have to go refill my oil lamp and change some bedpans...
> 
> jed peterson rn
> --
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