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Sun Nov 7 23:04:05 GMT 2004

The important thing to remember with pneumococcal vaccine is that it is the
polysaccharide vaccine that needs to be given to adults not the conjugate.
The poly. vaccine is 23 valent (conjugate in a 7 valent vaccine)& works best
in adults. An issue with pneumococcal revaccination is that you get a hypo
immune response from the booster doses (cast your minds back to vaccine
immunology 101).  Boosters can be given as early as three years apart, but
there is a significantly increased risk of severe local (not sure about
systemic) reactions.

On Errington's point about the epi of invasive pneumococcal disease, here in
Australia the National Centre for Immunisation Research & Surveillance
(NCIRS)is collecting case data on notified cases, and several laboratories
are also collecting serotype data  - I think the NCIRS has published data on
their findings to date, but I don't know if the serotype research has been
published as yet.

Rod Reynolds
Trauma Data Manager
Illawarra Trauma Service

The ultimate weapon is an educated mind

-----Original Message-----
From: trauma-list-bounces at trauma.org
[mailto:trauma-list-bounces at trauma.org]On Behalf Of
alcalaye at post.tau.ac.il
Sent: Saturday, 6 November 2004 7:51 AM
To: Trauma & Critical Care mailing list
Subject: RE: Pneumococcal vaccine

I clicked on the wrong number. It should be read:
> As far as I know - a booster is not required every 5 years but only once
> after 5 years:
> "Because data are insufficient concerning the safety of pneumococcal
vaccine
> when administered three or more times, revaccination following a second
dose
> is
> not routinely recommended" (copied from
> http://www.cdc.gov/epo/mmwr/preview/mmwrhtml/00047135.htm)
> Eli Alkalay
> Rural family physician
> Israel
>
> Quoting "Hardcastle Tim, Dr <tch at sun.ac.za>" <tch at sun.ac.za>:
>
> > ... Also remember that a booster is required every 5 years. ...
>
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Pneumococcal vaccine