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Erythropoietin in acute trauma
Alexander Chelnokov alex at orto.unets.ruWed Apr 21 11:01:41 BST 2004
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Hello Karim, Sunday, April 11, 2004, 12:07:01 AM, you wrote: KB> However there is a randomized double-blind controlled trial of EPO in KB> critically ill patients (JAMA 2002) which I've posted below. Basically this KB> multicenter study randomized 1302 patients to EPO or placebo on ICU day 3 Are the results relevant to acute trauma patients? Should we pay any attention to the level of the endogenous e-poietin? Maybe its production in chronic "critically ill" patients is supressed and the situation is different from acute trauma patients without severe pre-existed diseases? -- Best regards, Alexander N. Chelnokov Ural Scientific Research Institute of Traumatology and Orthopaedics 7, Bankovsky str. Ekaterinburg 620014 Russia
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