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Erythropoietin in acute trauma

Alexander Chelnokov alex at orto.unets.ru
Wed Apr 21 11:01:41 BST 2004


Hello Karim,

Sunday, April 11, 2004, 12:07:01 AM, you wrote:

KB> However there is a randomized double-blind controlled trial of EPO in
KB> critically ill patients (JAMA 2002) which I've posted below.  Basically this
KB> multicenter study randomized 1302 patients to EPO or placebo on ICU day 3

Are the results relevant to acute trauma patients? Should we pay any
attention to the level of the endogenous e-poietin? Maybe its production
in chronic "critically ill" patients is supressed and the situation is
different from acute trauma patients without severe pre-existed
diseases?

-- 
Best regards,
 Alexander N. Chelnokov
Ural Scientific Research Institute 
of Traumatology and Orthopaedics
7, Bankovsky str. Ekaterinburg 620014 Russia



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